Jeff's MELISA Results

In late October 1998, I had the "MELISA® Test For Metal Allergy" performed on samples of my blood. This blood was collected into special vacuum tubes, centrifuged, packaged at room temperature, and flown to Stockholm, Sweden along with the blood of three other people.

If you have completely waded through the accounts of my personal odyssey found on this website, then you know that my exposure to mercury via dental amalgam continued even after my initial "recovery". June 1997 is when the last of my amalgam hiding under gold crowns was finally removed. June 1997 to late October 1998 is one year and four+ months, lets call it a "year and half" later, that I had the MELISA test done. Except for what shows up in my normal air, water, and food, which is light on fish and seafoods, I have had no subsequent exposures to mercury.

As you can see below, I am still circulating memory lymphocytes programmed for inorganic mercury, the predominate metabolic end-form of all mercury that enters blood and tissues. The response is positive, but not strongly positive, which agrees with removal of the exposure source more than a year before, the mercury amalgam dental restorations. It is not much of a stretch to speculate that when I was still being exposed to mercury through amalgam, and symptomatic from that exposure, the lymphocyte response would have been recorded as higher.

My good fortune cannot be underestimated. Both my titanium implants, and my many gold restorations are tolerated by my immune system. Having stumbled through a dark, unlit room, filled with many obstacles and hazards, I have come out pretty much unscathed. The better way to have approached my dental work would have been to have had a MELISA test before removing all the amalgam and replacing it with gold alloys. In my case there had already been significant exposure to gold crowns, so a prospective test would have been meaningful for me, unlike my unfortunate friend described on the previous page.

What I have discovered new about myself is that I have a strong allergy to nickel. One of my metal crowns is believed to have been made from this metal. In fact, this was the last crown removed in the summer of 1997. There were bleeding gums around the crown, and other discomforts. The crown also harbored a chronically infected root canal, so it is difficult to assign specific symptoms to specific causes with this tooth. Nonetheless, nickel is a common metal found in most soils, is taken up by plants, and is almost impossible to totally eliminate from the diet. Nickel is a component of stainless steel, and enters food and liquids during cooking, water transport and storage. I'll save a longer discussion of nickel allergy for another page, but will say briefly here that I've since moved to glass cookware and filtered cooking and drinking water as part of my strategy for dealing with this metal.

With no further prelude, here are my personal MELISA results, reconstructed by me in html from the printed laboratory report. (Note: fractional notation is in European format: 2,5 = 2.5)

 MELISA® Laboratory
Danderyds Hospital
182 88 Danderyd
Sweden
         

 

 Patient code:

 

Jeff Clark

     
 Date of sample:  981022        
 Study:  9868        

 

Performed tests:

 

Al. Au, Pd, Pb, Cd, Hg, Ag, Ni, PhHg, Cu, TiCl4, Sn, Pt, MeHg, EtHg, and Sodium lauryl sulfate

 

Lymphocyte treatment

Cpm

Stimulation Index

Number of lymphoblasts

 Comments
Negative control

2146 +/- 598
 

1

2

Many activated MF

 

Lymphocyte treatment

 Conc. (ug/ml)

delta Cpm 

 Stimulation Index

 Number of lymphoblasts

 Comments
 PPD

1

6889

4,2

20
 

 

 Aluminum

 40

267

1,1

 -
 
 

 20

1591

1,7

0
 
 

 10

521

1,2

-
 

 

Gold

6,25

3724

2,7

9
 
 

 3,12

1182

1,6

0

Activated MF
 

 1,56

-187

0,9

-
 

 

Palladium

6,25

1055

1,5

-
 
 

 3,12

1182

1,6

-
 
 

 1,56

490

1,2

-
 

 

 Lead

25

477

1,2

-
 
 

12,5

1993

1,9

-
 

 

Cadmium

3,12

-100

1,0

-
 
 

1,56

1526

1,7

-
 
 

0,78

99

1,0

-
 

 

 Inorganic Hg

0,5

6241

3,9

40
 
 

0,25

4122

2,9

20
 
 

0,125

1464

1,7

-
 

 

 Silver

2,5

323

1,2

-
 
 

1,25

1842

1,9

-
 

 

 Nickel

5

22546

11,5

 >100
 
 

2,5

40596

19,9

>100
 
 

1,25

5489

3,6

-
 

 

 Phenyl-Hg

0,5

3675

2,7

8

Bad slide
 

0,25

3863

2,8

15
 
 

0,125

 3023

2,4

-
 

 

 Copper

0,5

-728

0,7

-
 
 

0,25

-249

0,9

-
 

 

 Titanium chloride

200

-725

0,7

-
 
 

100

-659

0,7

-
 
 

50

-187

0,9

-
 

 

 Tin

50

1551

1,7

-
 
 

25

-359

0,8

-
 
 

 12,5

-946

0,6

-
 

 

 Platinum

25

-677

0,7

-
 
 

12,5

214

1,1

-
 

 

 Methyl-Hg

0,5

-897

0,6

-
 
 

0,25

-731

0,7

-
 
 

0,125

-340

0,8

-
 

 

 Ethyl-Hg

0,5

980

1,5

-
 
 

0,25

-1145

0,5

-
 
 

0,125

-1079

0,5

-
 

 

 Sodium lauryl sulfate

100

640

1,3

-
 
 

50

109

1,1

-
 
 

25

1680

1,8

-
 

 

Footnote:

         
 CPM Counts per minute
 delta CPM Cpm in test cultures minus cpm in neg. control cultures
 SI Stimulation Index = cpm in test culture divided by the mean cpm in control cultures
 PPD Tuberculin, purified protein derivative = positive control
 - Not done
 MF Macrophages

 

 Evaluation:

         
 Strongly Positive to: Nickel        

 

 Positive to:

Inorganic Hg      

 

 Weakly positive to:

Phenyl-Hg      

 

 Negative to:

 

Aluminum
Gold
Palladium
Lead
Cadmium
Silver
Copper
Titanium chloride
Tin
Platinum
Methyl-Hg
Ethyl-Hg
Sodium lauryl sulfate

     

 

 Comments

 Low PPD response      

J.C. comments on PPD: PPD is a good choice for a positive control in European patients, since there has traditionally been a TB vaccination program in European countries. In the USA, public health officials seemed to have decided that TB vaccination was too risky, or unneeded. I've never been vaccinated for TB, and to my knowledge have not been exposed to the disease either. Another member of my group having MELISA tests once lived at home with a parent who had developed TB. She had even gone through extensive antibiotic treatments to avoid also developing the disease. She was the only member of our USA group who didn't have a low PPD response from MELISA, her PPD scores were: SI= 205, with lymphoblasts > 100.


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Copyright ©1999 Jeff Clark